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Cardiac Surgery Research

Clinical Research

Research is an integral part of our mission in the Weill Cornell Department of Cardiothoracic Surgery. We strive to understand the pathophysiologic mechanisms of cardiovascular disease, develop and improve treatment methodologies, and improve the quality of the care that we offer. We have an active clinical and translational research center that focuses on the major cardiovascular disorders including coronary artery disease, heart valve disorders, and aortic pathologies, such as aneurysms and other aortopathies.

Clinical Trials

Our department participates in numerous national trials sponsored by industry representatives. We participate in studies to evaluate a variety of novel cardiac implants, such as innovative heart valve implants, heart valve repair techniques, aortic grafts, ventricular assist devices, and end-organ preservation devices. Learn more

  • Aortic Disease

  • Coronary Artery Disease

  • Atrial Fibrillation

  • Valvular Disease

Our Researchers

<a href="">Leonard N Girardi, M.D.</a>

Leonard N Girardi, M.D.

Chairman of Cardiothoracic Surgery

<a href="">Mario FL Gaudino, M.D.</a>

Mario FL Gaudino, M.D.

Assistant Dean of Clinical Research;
Director of the JCTO;
Director of Translations and Clinical Research

<a href="">Stephanie L Mick, M.D.</a>

Stephanie L Mick, M.D.

Associate Professor of Cardiothoracic Surgery

<a href="">Christopher Lau, M.D.</a>

Christopher Lau, M.D.

Associate Professor of Cardiothoracic Surgery

<a href="">Erin Mills Iannacone, M.D.</a>

Erin Mills Iannacone, M.D.

Assistant Professor of Clinical Cardiothoracic Surgery

Director of Research Administration

Murtaza Malbari, MS

Murtaza Malbari, MS

Director of Research Administration
Phone: (212) 746-9400
Fax: (212) 746-9393


Dr. Mario Gaudino is the newly appointed director of the Joint Clinical Trials Office (JCTO) at Weill Cornell Medicine | NewYork-Presbyterian, Dr. Gaudino oversees ongoing clinical trials and lead strategic planning efforts.


The ROMA Trial

Dr. Gaudino is also one of the Principal Investigators of The ROMA Trial, a two-arm event-driven randomized multi-center trial aimed at evaluating the impact of the use of one ITA vs two or more AGs for CABG on a composite of death from any cause, any stroke, and post-discharge myocardial infarction and/or repeat revascularization.

Weill Cornell Medicine Cardiothoracic Surgery 525 East 68th Street
Box 110
Suite M 404
New York, NY 10065 Directions
Phone: (212) 746-5166


Reducing Copper in the Body Alters Cancer Metabolism to Reduce Risk of Aggressive Breast Cancer

Transmission electron microscopy images

Transmission electron microscopy images...

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TWIST - Designing an International Multi-center Trial

Evaluating therapeutic approaches through clinical research can be done at many different scales; some exploratory studies seek to enroll just a handful of participants at a single site while other ideas require a great deal more statistical power. Thankfully multi-center and international collaborations are an excellent source of that power! Join our Director Dr. Mario Gaudino on Tuesday August 17th for a look at his work and experience designing and running a trial that spans over 50...

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Q&A with Dr. Mario Gaudino, Newly Appointed Director of the Joint Clinical Trials Office

For Dr. Mario Gaudino, being an excellent cardiothoracic surgeon and conducting clinical research to find new ways to improve patients’ outcomes have been two sides of the same coin since he was a medical student in Rome. Today, he is a renowned surgeon treating patients with heart and cardiovascular disease, and at the same time, serves as the primary investigator of the ...

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