Coronary Artery Bypass Grafting Research

Randomized comparison of the clinical Outcome of single versus Multiple Arterial grafts: the ROMA trial

The ROMA trial is a randomized multi-center trial aimed at evaluating the impact of the use of one versus two or more arterial grafts for coronary artery bypass surgery. The Weill Cornell Department of Cardiothoracic Surgery is the primary sponsor of this multi-national study, which aims to evaluate the benefits of using multiple arterial grafts in CABG surgery to improve survival and reduce the rate of complications. Learn more

Radial Artery Database International Alliance

This project was conceived to overcome the limitations of the single studies published to date on the radial artery and to create a joint database including all the major RCTs and propensity matched observational studies. This joint database will allow sufficient statistical power to perform the first patient-level meta-analysis to evaluate the clinical benefits related to the use of the radial artery. If successful this project will be the first to show a RCT-based survival benefits with the use of a second arterial conduit during coronary artery bypass operations.

Radial Artery Harvesting Techniques

This project studies the effects of different harvesting techniques on the vascular integrity of the radial artery used for coronary artery bypass grafting. Open harvesting techniques are compared to endoscopic techniques. Histologically, we examine the endothelial integrity, vascular innervation, and nitric oxide synthase expression in the harvested grafts.


The Effect of Posterior Pericardiotomy on the Incidence of Atrial Fibrillation

Atrial fibrillation is a common complication after cardiac surgery and it requires either medical/electrical cardioversion or anticoagulation to prevent more serious sequelae. This study analyzes the efficacy of a posterior pericardiotomy in preventing postoperative atrial fibrillation after open cardiac surgery by allowing fluid in the pericardial sac to drain more easily into the pleural space.

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