November 7, 2016 8 am - 9 am Uris Auditorium James D. Luketich, M.D. Henry T. Bahnson Professor of Surgery Chairman, Department of Cardiothoracic Surgery Chief, Division of Thoracic and Foregut Surgery University of Pittsburgh Medical Center
Breast cancer cells do not undergo a commonly accepted transformation in order to spread to distant organs such as the lungs, Weill Cornell Medicine investigators have found in a new study. This discovery may settle a longstanding debate about how cancers spread, the investigators say, and may profoundly change the way many forms of the disease are treated.
Understanding Crosstalk in Tumor Microenvironment Could Lead to New Precision Medicine Approaches
Many patients with non-small cell lung cancer (NSCLC) have no identifiable mutations, and therefore their disease cannot be managed with targeted treatments. These patients often experience disease progression despite chemotherapy. However, a study led by investigators at Weill Cornell Medical College used a new approach to examine crosstalk between cancer cells and cells in the microenvironment in NSCLC. Instead of looking at the tumor as a whole, the researchers used deep sequencing of RNA to analyze individual cell populations isolated from NSCLC specimens, an approach that could someday lead to new treatments for patients with NSCLC.