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The Department of Cardiothoracic Surgery is a recognized leader in heart, lung and esophagus surgery. Our experience with complex cardiothoracic issues and knowledge of the latest advances have helped to establish NewYork-Presbyterian|Weill Cornell Medicine as a major referral center for cardiovascular and thoracic patients from around the world.

Cardiothoracic surgery group photo

Cardiac Surgery

The Division of Cardiac Surgery provides expert care to patients who need:

  • Coronary artery bypass surgery
  • Valve repair/replacement
  • Surgery for adult congenital heart disease
  • Minimally Invasive Heart Surgery
  • Ventricular Assist Devices (VADs)
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Cardiac Surgery team

Thoracic Surgery

The Division of Thoracic Surgery offers the most advanced surgical care for:

  • Lung and esophageal cancers
  • Emphysema
  • Hyperhidrosis
  • Hiatal hernia
  • Pericardial & Pleural Effusions
  • Thoracentesis
Learn More
Thoracic Surgery team

Why Choose Weill Cornell?

NewYork-Presbyterian & Weill Cornell Medicine - Cardiothoracic Surgery

New Advances

Reducing Copper in the Body Alters Cancer Metabolism to Reduce Risk of Aggressive Breast Cancer

Transmission electron microscopy images

Transmission electron microscopy images showing TM-mediated changes in the cristae (arrow) inside the mitochondria of cancer cells, which contribute to cellular metabolism. Image courtesy of Dr. Divya Ramchandani, Juan Pablo Jimenez and Leona Cohen-Gould.

Depleting copper levels may reduce the production of energy that cancer cells need to travel and establish themselves in other parts of the body by a process referred to as metastasis, according to a new study by investigators from Weill Cornell Medicine and Memorial Sloan Kettering Cancer Center (MSK). The discovery of the underlying mechanisms of how copper depletion may help reduce metastasis in breast cancer will help inform the design of future clinical trials.

In a series of research papers from 2013 to 2021, Weill Cornell Medicine researchers showed that in a phase II clinical trial when patients who had high-risk triple-negative breast cancer (TNBC) were treated with a drug that lowers the levels of copper in their bodies, it prolonged the period of time before their cancer recurred and spread or metastasized. In the current study, published Dec. 15 in Nature Communications, and led by first author Divya Ramchandani, a research associate in Cardiothoracic Surgery at Weill Cornell Medicine, the investigators used animal models to take a closer look at why that was the case. Click here to read the full article. 

Simple Surgical Technique Associated with Significant Reduction in the Risk of Atrial Fibrillation After Cardiac Surgery

Mario Gaudino, MD

Dr. Mario Gaudino

 

A simple surgical technique during cardiac surgery was associated with a 56 percent reduction in the incidence of an irregular heart rhythm known as atrial fibrillation that can lead to stroke, with no added risks or side effects, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators. The findings suggest that the method, called posterior left pericardiotomy, has significant potential for preventing prolonged hospital stays and the need for additional interventions and drugs to reduce the risk of strokes and heart failure associated with atrial fibrillation.

The study evaluated whether a posterior left pericardiotomy, a slit in the backside of the sac around the heart to drain excess fluid, could help prevent atrial fibrillation in patients who underwent cardiac surgeries. The randomized controlled trial was published Nov. 14 in The Lancet. Click here to read the full article.

Healthgrades specialty hospital rankings

Healthgrades rates NewYork-Presbtyerian and Weill Cornell as America's 50 Best Hospitals for Cardiac Surgery Award.  Superior Clinical Outcomes in Heart Bypass and Heart Valve Surgery.  

Healthgrades rates NewYork-Presbtyerian and Weill Cornell as America's 100 Best Hospitals for Cardiac Care Award.  Superior Clinical Outcomes in Heart Bypass, coronary interventional procedures, heart attack treatment, heart failure treatment, and heart valve surgery

Scientists Find a New Way to Reverse Immune Suppression in Tumors

two men posing for a photo

Drs. Vivek Mittal (left) and Dingcheng Gao

Malignant tumors can enhance their ability to survive and spread by suppressing antitumor immune cells in their vicinity, but a study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian has uncovered a new way to counter this immunosuppressive effect.

In the study, published Sept. 20 in Nature Cancer, the researchers identified a set of anti-immunosuppressive factors that can be secreted by cells called club cells that line airways in the lungs. They showed in a mouse model of lung cancer that these club cell factors inhibit highly potent immunosuppressive cells called myeloid-derived suppressor cells (MDSCs), which tumors often recruit to help them evade antitumor immune responses.

The inhibition of the MDSCs led to an increase in the number of antitumor T cells at the tumor site, and greatly improved the effectiveness of FDA approved PD1 immunotherapy. 

“These club cell-secreted factors are able to nullify immune suppressor cells that otherwise help tumors escape an effective antitumor response,” said co-senior author Dr. Vivek Mittal, director of research at the Neuberger Berman Lung Cancer Center and the Ford-Isom Research Professor of Cardiothoracic Surgery at Weill Cornell Medicine. “We’re excited by the possibility of developing these club cell factors into a cancer treatment.” Click Here to read the full article. 

Clinical Trials

The Cardiothoracic Surgery Department conducts a robust clinical trials program to evaluate the effectiveness of new treatments and medications that have the potential to improve the management of patients with heart, lung, and esophageal disease. The outcomes of heart, lung, and esophageal operations can be improved with technical innovations.

Current Clinical Trials

 

US News Cardiology & Heart Surgery Badge Best regional hospital 2022                       

Ranked #4 in Adult Cardiology & Heart Surgery Hospital in the nation and #1 in NYC by U.S. News and World Report

Ranked #1 in Best Regional Hospitals in U.S. News

          

      50 Best Cardiac Surgery badget              100 Best Cardiac Surgery

America’s 50 Best Hospitals for Cardiac Surgery Award™ by Healthgrade

America’s 100 Best Hospitals for Cardiac Care Award™ by Healthgrade