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Gold Nanoparticle Delivery of MicroRNA Impairs Metastasis in Triple-Negative Breast Cancer

lung cancer, thoracic surgery, Neuberger Berman Lung Cancer Research Center, Vivek Mittal

Dr. Vivek Mittal. Credit: John Abbott



Weill Cornell Medicine researchers have shown that giving mice with triple-negative breast cancer therapeutic microRNA (miRNA) in a protective gold nanoparticle results in significantly less spreading of cancer to the lung. Triple-negative breast cancer is a highly aggressive, difficult-to-treat form of the disease, with a high rate of metastatic recurrence. miR-708 is a non-coding microRNA that can block expression of genes that are crucial in metastasis.

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